# drug-pipeline

## Quick Start

```bash
# Connect this server (installs CLI if needed)
npx -y smithery mcp add crop-mcp/drug-pipeline

# Browse available tools
npx -y smithery tool list crop-mcp/drug-pipeline

# Get full schema for a tool
npx -y smithery tool get crop-mcp/drug-pipeline search_trials

# Call a tool
npx -y smithery tool call crop-mcp/drug-pipeline search_trials '{}'
```

## Direct MCP Connection

Endpoint: `https://drug-pipeline--crop-mcp.run.tools`

**Optional config:**
- `default_drug` (query) — Standard-Wirkstoff für Schnellabfragen
- `language` (query) — Ausgabesprache
- `max_trials` (query) — Maximale Anzahl klinischer Studien pro Suche

## Tools (12)

- `search_trials` — Search ClinicalTrials.gov for clinical trials by medical condition, phase, status, sponsor, or intervention. Returns NC…
- `get_trial_detail` — Get the complete protocol for a specific clinical trial by NCT ID. Includes eligibility criteria, primary/secondary out…
- `lookup_drug` — Look up a drug by brand or generic name. Returns active ingredients, strength, labeler/manufacturer, NDC number, RxNorm…
- `get_approvals` — Get the FDA approval history for a drug. Returns application numbers, sponsor name, and all submissions with status (ap…
- `search_publications` — Search PubMed for scientific publications related to a drug, condition, or clinical trial. Returns PMIDs, titles, journ…
- `drug_pipeline` — **Composite intelligence tool** — Combines drug lookup, FDA approval status, EU/EMA approval status, adverse event safe…
- `get_eu_approvals` — Get EU/EMA approval status for a drug by brand name or active substance. Queries the EMA Human Medicines Register (dail…
- `get_safety_data` — Get FDA Adverse Event Reporting System (FAERS) data for a drug. Returns total number of adverse event reports, the most…
- `approved_for_condition` — Find EU-approved drugs for a medical condition. Queries the EMA Human Medicines Register to return drugs authorized for…
- `get_trial_results` — Get results for a completed clinical trial by NCT ID. Returns outcome measures (primary and secondary endpoints with nu…
- `list_orphan_drugs` — List drugs with EU Orphan Drug Designation from the EMA register. Orphan designation means the drug treats a life-threa…
- `company_pipeline` — Get the complete clinical pipeline for a pharmaceutical company. Searches ClinicalTrials.gov for all studies sponsored …

```bash
# Get full input/output schema for a tool
npx -y smithery tool get crop-mcp/drug-pipeline <tool-name>
```

## Resources

- `ema://medicines` — EU Medicines database: aktuelle EMA-Zulassungen, Indikationen, Wirkstoffe

## Prompts (3)

- `drug-pipeline` (drug_name) — Full pipeline for a drug: FDA approvals + EU status + safety + trials + publications
- `trial-search` (condition, phase) — Find clinical trials for a condition with phase/status filters
- `safety-review` (drug_name) — Safety profile for a drug: adverse events, reactions, outcomes